when i use the clean channel, i have the highs set to 8, mids at 5, lows at 3. but some clean channels, including mine, are a little too powerful to play at loud volumes, so i often use my overdrive channel, turn the drive down to like 2 or 3, really low, and bring up the volume. there's no noticible distortion, so it sounds like a clean channel, and because the signal goes through the drive channel, it adds a bit of natural compression so the volumes are balanced whether you play in the low or high registers at really high volumes.