Sure.[br]General rule of thumb is 10,000 hours of practice to get "really good" at something, no matter what. Granted, some things are easier to learn for a young person, but not all. I'd say somebody who starts playing golf as a full time hobby at age 45 can become a world class golfer if he has also talent. A tennis star, not so much, as it involves a lot of physical activity. A guitarist? Of course!

If you have put 10,000 hours into learning the guitar, you may arrive at this stage:

https://www.youtube.com/watch?v=nMcdhCR9Ubw

No idea how much better you could become. The young chap did it in 7 years, so if you start out at 50, you may still be able to wow a large crowd many years before you retire.

A totally different hurdle is to publish, become a recording artist. The best age for that is in your teens. By age 30 the train has often left the station. That has nothing to do with talent, but everything to do with cultural habits.